Impact of mirna in atherosclerosis
Witryna18 gru 2013 · By using a technology called "locked nucleic acids," Jo and his colleagues tested the effects of blocking miR-712 in the body. When given to mice in the rapid atherosclerosis model, the anti-miR-712 drug inhibited the development of arterial blockages. Without the drug, plaques blocked an average of 80 percent of the … Witryna17 gru 2024 · This study presents novel evidence linking miR-155 biology with the progression and regression of atherosclerosis. Herein, we have shown an inverse …
Impact of mirna in atherosclerosis
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Witryna15 maj 2014 · The effect of miR-126-5p on atherosclerosis has been identified in vivo, which controls differentiation of smooth muscle cells, promotes lesion formation, whereas the endothelial cell-specific miR ... Witryna22 sie 2024 · MicroRNA regulation of atherosclerosis. Circ Res. 2016; 118:703–720. doi: 10.1161/CIRCRESAHA.115.306300 Link Google Scholar; 118. Eken SM, Jin H, Chernogubova E et al.. MicroRNA-210 enhances fibrous cap stability in advanced atherosclerotic lesions. Circ Res. 2024; 120:633–644. doi: …
Witryna22 sie 2024 · Impact of miRNA in Atherosclerosis. miRNAs have received most of the attention during the last decades in particular for their role in tempering gene … WitrynaHere, we aimed to screen the atherosclerosis-associated miRNAs and preliminarily investigate the potential regulatory mechanism of... Endothelial Cells, Atherosclerosis and Mesenchymal Cells ...
Witryna14 lis 2024 · MiR-495 had an effect on endothelial cell proliferation and migration pathways by repressing CCL2 expression (Hartmann et al. 2015) and miR-495 inhibition could decrease accelerated atherosclerosis and increase plaque stability, contributing to the prevention of restenosis (Welten et al. 2024). WitrynaAtherosclerosis is a hallmark of cardiovascular disease, and lifestyle strongly impacts its onset and progression. Nutrients have been shown to regulate the miR-17/92 cluster, with a role in endothelial function and atherosclerosis. Choline, betaine, and L-carnitine, found in animal foods, are metabolized into trimethylamine (TMA) by the gut …
Witryna14 kwi 2024 · It should be noted that miR-10b expression is altered in whole human arteries affected by atherosclerosis [37, 40]. Mir10b knockout mice were resistant to …
Witryna24 mar 2024 · Atherosclerosis (AS) is a chronic arterial disorder and a significant determinant of vascular death [].Fatty streaks in arterial walls regularly develop into characteristic plaques and atheroma [].The acute rupture of these atheromatous plaques leads to local thrombosis, causing partial or total occlusion of the affected artery [].AS … durham msc chemistryWitrynaMiRNA controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-γ, and plays the roles in endothelial cell (EC), vascular smooth … cryptoconftWitryna19 lut 2016 · Over the past decade, microRNAs (miRNAs) have emerged as evolutionarily conserved, noncoding small RNAs that serve as important regulators … cryptoconflict.joycityWitryna19 lut 2016 · The recent emergence of microRNAs (miRNAs) as important regulators of pathophysiological processes, such as cellular adhesion, proliferation, lipid uptake … durham msc physicsWitryna13 paź 2024 · They have potential regulatory effects on atherosclerosis and vascular endothelial injury by targeting miR-30d-3p-TP53RK and miR-140-3p-MKK6 axis and … durham msc mathematicsWitrynaMoreover, miRNAs are present in peripheral blood with high stability and have the potential to be used as non-invasive biomarkers for the diagnosis of atherosclerosis. However, the circulating miRNA profile may vary according to the involved arterial territory, considering that atherosclerosis expression, including the associated … durham msc financial mathematics ukWitryna20 mar 2013 · MicroRNAs (miRNAs) are small, ~22 nucleotide (nt) sequences of RNA that regulate gene expression at posttranscriptional level. These endogenous gene expression inhibitors were primarily described in cancer but recent exciting findings have also demonstrated a key role in cardiovascular diseases (CVDs), including … durham motorcycle safety course