WebINCB106385, also known as INCB-106385, is a cancer drug with 2 actively recruiting clinical trials and 0 FDA/NCCN therapies. WebDec 1, 2024 · Key Highlights of the Adenosine Receptors (A2a/A2b) Antagonists Report: There are ~8 products in the Phase 1 stage of development, representing 29.63% of the total share of the developing A2aR/A2bR Antagonist landscape. The remaining 70.37% has been contributed by Phase 2 (18.52%), Phase 1/2 (14.81), Pre-clinical (18.52%), and Discovery …
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WebApr 10, 2024 · Domvanalimab (AB154), an anti-TIGIT monoclonal antibody and new potential immuno-oncology backbone therapy, is in a three-arm randomized Phase 2 study for first-line treatment of PD-L1 ≥ 50%... WebINCB-106385 Etrumadenant Ciforadenant Selatogrel TT-4 TT-10 DZD-2269 Ciforadenant Table of Contents Introduction Executive Summary Purinergic Receptor (Purinoceptor) Antagonists: Overview Causes Mechanism of Action Signs and Symptoms Diagnosis Disease Management Pipeline Therapeutics Comparative Analysis Therapeutic Assessment dhhs health equity
INCB
WebINCB106385 is a small molecule that has been designed to moderate the activity of certain “messenger” molecules involved in the body’s immune response, called adenosine. Adenosine prevents the immune system from targeting and destroying healthy tissue; however, it can also prevent the immune system from targeting and destroying cancer cells. WebNov 21, 2024 · INCB-106385 is under development for the treatment of solid tumors including ovarian cancer, bladder cancer, non small cell lung cancer, squamous cell … WebDrug Name: INCB106385: Trade Name: Synonyms: INCB-106385 INCB 106385: Drug Descriptions: INCB106385 is a dual inhibitor of A2A and A2B receptors, which may prevent immune suppression in the tumor microenvironment and promote anti-tumor immune response (AACR Annual Meeting Apr 2024, Session PO.IM02.03, Abstract # LB157). dhhs health care technician i rate