Smad4 sc-7966
WebbSmad4 is a tumor suppressor gene that is commonly lost or mutated in colorectal and pancreatic cancers. The activated transforming growth factor-b (TGF-b)receptor Webb1 juli 2013 · Because Smad4 is a central signaling molecule of TGF-β–induced signal transduction, we hypothesized that nestin expression status might depend on TGF-β1/Smad4 signaling. Nestin promoted tumor cell migration and induced EMT in PDAC We investigated whether nestin played a direct functional role in facilitating PDAC cell …
Smad4 sc-7966
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WebbFigure Legend Snippet: Clobetasol propionate (CP) dose-dependently induces senescence and collagen synthesis decrease in human dermal fibroblasts (HDFs). Cells were treated … Webb18 nov. 2016 · Although Smad4 clearly has crucial roles in skeletal muscle and tissue-specific stem and progenitor cell biology, to date no studies have explicitly examined whether or not there is a cell-autonomous requirement for Smad4 in SCs and derived MPs during skeletal muscle regeneration.
Webb25 maj 2024 · SMAD4, a key regulator of transforming growth factor-β (TGF-β) signaling, plays a major role in cell growth, migration, and apoptosis. In particular, TGF-β/SMAD … WebbAntibody: Clone Number: Purification: unknown how antibody is supplied Isotype: IgG1: Host Organism: mouse: Xenopus Reactivity: tropicalis, laevis
WebbSAN TA C RUZ BI OTEC HNOL OG Y, INC . Smad4 (N-16): sc-1908 SantaCruzBiotechnology,Inc. 1.800.457.3801 831.457.3800 fax 831.457.3801 Europe +00800 4573 8000 49 6221 4503 0 www.scbt.com BACKGROUND Smad proteins, the mammalian homologs of the Drosophila mothers against dpp (Mad) have been … WebbWestern blot was performed to detect the knockout effect using SMAD4 antibody (Santa Cruz Biotechnology, Inc. sc-7966). The PaCa DD183 cell line was derived from a …
Webb27 aug. 2012 · In situ proximity ligation assays showed that TGFβ signaling not only induces complexes between Smad3 and Smad4 in the nucleus but also complexes between Smad2/3 and Fra1, whereas complexes...
Webb1 okt. 2010 · Paraffin sections (7.5 μm thick) were incubated with the following primary antibodies: Anti-Smad4 (sc-7966, Santa Cruz Biotechnology, CA), Rabbit polyclonal anti … birth of the royal ulster constabularyWebb1 okt. 2010 · Paraffin sections (7.5 μm thick) were incubated with the following primary antibodies: Anti-Smad4 (sc-7966, Santa Cruz Biotechnology, CA), Rabbit polyclonal anti-alpha and anti-beta Crystallin antibodies provided by Dr. Samuel Zigler (John Hopkins University, MD) for 1 h at 37 °C following antigen retrieval and blocking. birth of the royal marinesWebb7 Table S7. Antibodies Rabbit anti Rabbit anti Mouse anti Antibodies Company Dilution Rabbit anti-Kras polyclonal antibody ab180772 Abcam 1:100 Rabbit anti-p16 monoclonal … darby\\u0027s accountants retfordWebbBiotechnology (Smad4 [sc-7966]). siRNA was purchased from ThermoFisher Scientific (Smad3 [VHS41114]), Dharmacon (Smad2 [L-003561-00]), and Qiagen (RhoA … birth of the saviorWebbCheck out videos that might be relevant for performing Western blotting Smad4 using Smad4 Antibody (B-8): sc-7966 from Santa Cruz Biotechnology. Please note that these … birth of the seaWebb2 sep. 2024 · Smad4 serves as a tumor modulator by monitoring chemoresistance, angiogenesis, and vessel hyperpermeability. 15 - 17 Ozawa et al. 18 found that Smad4 … darby\\u0027s accountants gainsboroughWebb14 mars 2014 · SMAD4 is a gastrointestinal malignancy-specific tumor suppressor gene found mutated in one third of colorectal cancer specimens and half of pancreatic … darby\\u0027s accountants worksop