The profher trial
WebbBackground Proximal humerus fractures (PHF) are common and painful injuries, with the majority resulting from falls from a standing height. As with other fragility fractures, its age-specific incidence is increasing. Surgical treatment with hemiarthroplasty (HA) and reverse shoulder arthroplasty (RSA) have been increasingly used for displaced 3- and 4-part … WebbAims: A pragmatic multicentre randomised controlled trial (PROFHER) was conducted in United Kingdom National Health Service (NHS) hospitals to evaluate the clinical …
The profher trial
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Webb21 dec. 2024 · The ProFHER (PROximal Fracture of the Humerus: Evaluation by Randomisation) trial – a pragmatic multicentre randomised controlled trial evaluating the clinical effectiveness and cost-effectiveness of surgical compared with non-surgical treatment for proximal fracture of the humerus in adults Handoll, et al. (2015) Health … WebbThe ProFHER (PROximal Fracture of the Humerus: Evaluation by Randomisation) trial – a pragmatic multicentre randomised controlled trial evaluating the clinical effectiveness and cost-effectiveness of surgical …
WebbThe ProFHER (PROximal Fracture of the Humerus: Evaluation by Randomisation) trial – a pragmatic multicentre randomised controlled trial evaluating the clinical effectiveness and cost-effectiveness of surgical … Webb1 mars 2015 · DOI: 10.3310/hta19240 Corpus ID: 23129517; The ProFHER (PROximal Fracture of the Humerus: Evaluation by Randomisation) trial - a pragmatic multicentre randomised controlled trial evaluating the clinical effectiveness and cost-effectiveness of surgical compared with non-surgical treatment for proximal fracture of the humerus in …
WebbHandoll H, Brealey S, Rangan A, et al. The ProFHER (PROximal Fracture of the Humerus: Evaluation by Randomisation) trial – a pragmatic multicentre randomised controlled trial evaluating the clinical effectiveness and cost-effectiveness of surgical compared with non-surgical treatment for proximal fracture of the humerus in adults. WebbBackground/aims: There is growing interest in the use of adaptive designs to improve the efficiency of clinical trials. We apply a Bayesian decision-theoretic model of a sequential experiment using cost and outcome data from the ProFHER pragmatic trial. We assess the model's potential for delivering value-based research.
WebbOBJECTIVES: To explore whether orthopaedic surgeons have adopted the Proximal Fracture of the Humerus: Evaluation by Randomisation (PROFHER) trial results routinely into clinical practice. METHODS: A questionnaire was piloted with six orthopaedic surgeons using a 'think aloud' process. The final questionnaire contained 29 items and was …
Webb3 rader · 1 dec. 2024 · The PROFHER-2 Trial continues to include new participants and follow-up existing participants ... cult charactersWebb1 mars 2015 · The ProFHER (PROximal Fracture of the Humerus: Evaluation by Randomisation) trial – a pragmatic multicentre randomised controlled trial evaluating … cult children of godWebb16 nov. 2009 · The PROFHER trial is funded by the NHS R&D Health Technology Assessment Programme (HTA). The trial sponsor is the Teesside University, Middlesbrough, UK. Feedback on trial design and implementation, and support for the trial have been obtained over a protracted period from a large number of people. east herts blue badge applicationWebbHelen Handoll 1, *, Stephen Brealey 2, Amar Rangan 3, Ada Keding 2, Belen Corbacho 2, Laura Jefferson 2, Ling-Hsiang Chuang 4, Lorna Goodchild 5, Catherine Hewitt 2, David … cult chinese dumplingsWebbPROFHER has had an impact on surgeons' clinical practice, both through changing it, and through underpinning existing non-operative practice. Although some respondents … east herts bowls league competitionsWebb13 maj 2016 · A pragmatic, multicenter, parallel-group, randomized clinical trial, the Proximal Fracture of the Humerus Evaluation by Randomization (PROFHER) trial, recruited 250 patients aged 16 years or older ... east herts bowls leagueWebb18 sep. 2024 · PROFHER was a pragmatic, multi-centre RCT, funded by the National Institute for Health Research (NIHR) (UK), that compared surgical with non-surgical treatment in adults with displaced fractures of the … east herts brown bin payment